Postdoctoral Research Fellow in Medicinal Chemistry for Cancer Drug Discovery: Postdoctoral position is available in the laboratory of Prof. Tomasz Cierpicki, University of Michigan, Ann Arbor, to develop small molecule inhibitors for targeted therapies in cancer.
The lab seeking for highly motivated synthetic organic chemists and medicinal chemists to join a comprehensive drug discovery program.
About Grembecka/Cierpicki Lab
Dr Cierpicki’s lab. is conducting highly interdisciplinary research focused on pre-clinical development of novel anti-cancer drugs, which covers medicinal chemistry, structural biology, biochemical and biophysical assays, biological and animal studies. A strong team of synthetic chemists to support our drug-discovery efforts.
The successful candidate will be involved in designing and synthesis of small molecule inhibitors targeting proteins as potential anti-cancer agents with a major focus on the synthesis of heterocyclic compounds targeting protein-protein interactions relevant to cancer.
Responsibilities
The duties will include the design and synthesis of new analogues of existing leads to develop biologically active compounds for testing in cancer cells and animals.
The candidate must be independent in designing synthetic routes, solving challenging synthetic problems, efficient in synthesizing targeted molecules, including multi-step synthesis.
Requirements of Research Fellow in Medicinal Chemistry
Applicant must have a PhD in synthetic organic chemistry or medicinal chemistry and be a first author on at least 2-3 publications.
This position requires extensive experience in designing synthetic routes for new classes of compounds, solving challenging synthetic problems, SAR analysis.
The applicant needs expertise in using HPLC, NMR and MS for organic chemistry applications. Excellent oral and written communication skills in English are required.
How to apply
Please submit a cover letter, CV, and contact information for 2-3 references combined into one PDF file by e-mail to [email protected].
